Principal IS Application Analyst
- Dana-Farber Cancer Institute
- 450 Brookline Ave, Boston, MA 02215
- Nov 11, 2025
Job Description
Overview
This Principal IS (Information Systems) Application Analyst supports DFCI Information Services department systems and applications for the DFCI Radiation Oncology clinical department. The IS Principal Application Analyst will lead application deployment, configuration, system upgrades and maintenance for the many applications within the department. The role will continuously develop and implement process improvements that focus on optimizing operational efficiency, patient safety, and the quality of care. These functions are accomplished through participation in departmental projects with interdisciplinary teams that focus on workflow efficiency, clinical procedures, and applications training. Additionally, the IS Principal Application Analyst position requires a strong understanding of clinical workflows, excellent analytical and communication skills, and experience working with technical systems and interfaces.
The Radiation Oncology Information Systems team works solely to support the complex and technologically advanced Radiation Oncology Department at Dana-Farber Cancer Institute and associated satellite and outreach sites.
Incumbent will report to the Dana-Farber Cancer Institute Director, Technology Strategy and Solutions for Radiation Oncology in the Information Services (IS) department.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities
Application Duties
- Conduct thorough evaluations of current software applications to assess functionality, performance, and user satisfaction.
- Identify and document shortcomings or areas for improvement within existing applications to better meet organizational needs.
- Serve as the top technical and functional subject-matter expert; resolve the highest-severity incidents, perform root cause analysis, and implement preventative controls and resiliency patterns.
- Own enterprise-level application domains and cross-application architecture; define and steward standards for configuration, integrations, data, security, testing, and release management.
Project Leadership and Collaboration
- Translate business strategy into application roadmaps; partner with product owners and business leaders to prioritize portfolio and backlogs based on value, risk and feasibility.
- Work closely with customers to define business needs and develop project work approach, scope and timeline to meet both system and operational objectives.
- Participate in IS and clinical department projects, system upgrades and system enhancements utilizing standard project lifecycle tools and methodologies.
Process Improvement
- Lead and supports process improvement and new technology initiatives
- Continual evaluation of existing workflows to identify inefficiencies and areas of improvement.
- Explores external vendors and internal resources for improvement opportunities surrounding clinical department applications, and operational support.
- Define and track KPIs/OKRs for application performance, reliability, and adoption; champion continuous improvement and post-implementation value realization.
Training Duties
- Collaborate to design and implement training and professional development activities so that work is conducted in thoughtful planned manner
- Triage and prioritize training requests and recommend appropriate instructional methods such as individual or group instruction, lectures, online learning, hands-on workshop, or printed materials.
- Serve as Administrator for online learning management system (e.g. HealthStream). May include managing accounts, creating and maintaining online courses and curricula, running and analyzing reports, and leading troubleshooting when necessary.
Vendor and Stakeholder Management
- Manage vendor relationships for critical platforms; evaluate solutions, influence vendor roadmaps, oversee escalations, and ensure contractual SLAs and support models meet business needs.
- Align support efforts with organizational IT and clinical operations.
Supervisory Responsibility:
- May indirectly provide leadership and guidance to less seasoned and new staff as well as oversee resources on project work.
Qualifications
- Bachelor's degree in Information Systems, Computer Science, Healthcare Informatics, or a related field required.
- Master's degree preferred.
- 8+ years of direct experience with applications in a healthcare or Radiation Oncology or Radiology setting required.
- Experience with business process improvement, system-to-system interfaces, troubleshooting, and application upgrades preferred.
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:
- Deep expertise across multiple enterprise applications and modules, including advanced configuration, workflow design, and end-to-end solution integration.
- Skilled at managing and implementing change, particularly in quality improvement or process improvement initiatives.
- Operate with high autonomy, set direction and practices, mentor others, and drive adoption across teams; translate strategy into executable roadmaps and measurable outcomes.
- Excellent interpersonal, verbal and written communications skills to effectively work with various hospital departments, end users, senior leadership and IT department support teams.
- Comfort with ambiguity, rigorous impact/risk analysis, and making clear trade-offs that balance speed, cost, risk, and quality.
- Proficient in Microsoft Office applications and scheduling tools (e.g: Microsoft Project or Smartsheet).
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA)
$124,300 - $140,300
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff that offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
The Opportunity to Change a Life Begins with Dana-Farber!
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With a career at Dana-Farber Cancer Institute, you play an important role in helping to fulfill our mission and ultimate goal: the eradication of cancer and related diseases. We are ranked as one of the nation's best midsize employers and offer exciting jobs and careers to match your skills, interests, and passions.
The mission of Dana-Farber Cancer Institute is to provide expert, compassionate care to children and adults with cancer while advancing the understanding, diagnosis, treatment, cure, and prevention of cancer and related diseases.
As an affiliate of Harvard Medical School and a Comprehensive Cancer Center designated by the National Cancer Institute, the Institute also provides training for new generations of physicians and scientists, designs programs that promote public health particularly among high-risk and underserved populations, and disseminates innovative patient therapies and scientific discoveries to our target community across the United States and throughout the world.
