73 research technician jobs found in Boston, MA

The Romee lab described human memory-like NK cells with enhanced anti-tumor activity and in a first in human clinical trial demonstrated safety and promising activity of these cells in advanced AML patients. We are currently testing these memory-like NK cells in combination with novel immune-modulatory agents in patients with advanced malignancies including AML, MDS, platinum refractory head and neck cancer and multiple myeloma. Using flow cytometry, mass cytometry and single cell RNA sequencing on the samples collected from these studies allows us to study key aspects of the in vivo biology of the adoptively transferred memory-like NK cells and their interaction with other immune cells present in the tumor microenvironment. We hope this information will guide us in designing future NK cell based clinical protocols. The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, they...

Exciting opportunity for a motivated research technician to join the Ritz Lab. A dynamic position opening for a candidate to engage in cutting edge translational research on immune reconstitution in patients having undergone bone marrow transplantation for hematological malignancies. Bench work is followed up with flow cytometry instrumentation and state of the art software for data analysis. We look forward to you joining our team! The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer,...

The Freed-Pastor laboratory at Dana-Farber Cancer Institute and Harvard Medical School is seeking a highly-motivated, creative, and collaborative full-time Research Technician to join their team. The Freed-Pastor lab investigates how pancreatic cancer escapes immune eradication by leveraging in vivo animal model systems and ex vivo organoid cultures. Using these molecular insights paired with robust preclinical evaluation, we work closely with clinical colleagues to bring the most promising basic science discoveries from the lab to the clinic. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health...

The Viswanathan lab at the Dana-Farber Cancer Institute uses genomic and cutting-edge genome-scale functional genetic technologies to uncover drivers of genitourinary malignancies, with a specific focus on prostate and kidney cancers. We are in search of a highly motivated and experienced Research Technician / laboratory manager to join the Viswanathan laboratory. The projects will involve mechanistic study of genitourinary cancers (specifically kidney cancer) with the goal of developing insights that can be translated into novel therapeutics and improved outcomes for patients with these cancers. Responsibilities will include carrying out a research project related to the pathogenesis of kidney cancer under the close mentorship of senior postdoctoral fellows/staff and the principal investigator. In addition, there will be responsibilities related to lab management/administration, including maintenance of laboratory equipment and reagent inventories and reagent ordering, as...

The Research Technician will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard...

The Bandopadhayay Lab (www.bandolab.org) at DFCI (with co-affiliations with Boston Children’s Hospital and the Broad Institute) is seeking a motivated research assistant to join our efforts to find better treatments for children with brain tumors. We apply cutting-edge genomic technologies to identify drivers of childhood cancers and to determine mechanisms of resistance to current and novel treatments. Our lab is highly translational and spans efforts from acquiring patient samples to generating and analyzing high-throughput datasets from those samples. To that end, the individual will engage in experiments that utilize molecular biology techniques such as cell culture methods, recombinant DNA and gene transfer technology, and other cell biology assays. There will be opportunities to learn and assist in computational methods of analysis. The individual will also assist in daily laboratory operations and organization. Located in Boston and the surrounding communities, Dana-Farber...

The Research Technician position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical...

The Oser Laboratory in the Division of Molecular and Cellular Oncology and the Department of Medical Oncology at the Dana-Farber Cancer Institute/Harvard Medical School focuses on identifying new therapeutic targets in small cell lung cancer (SCLC). SCLC is a highly aggressive neuroendocrine cancer that is driven by loss of function (LOF) mutations in the tumor suppressor genes RB1, TP53, and NOTCH. It is also characterized by high expression of oncogenic neural/neuroendocrine transcription factors including ASCL1, NEUROD1, and POU2F3, which are dependencies in SCLC, but are undruggable. Our lab utilizes several approaches including CRISPR/Cas9-based functional screening and developing genetically-engineered mouse models of SCLC using CRISPR/Cas9 to identify novel ways to target LOF mutations in tumor suppressor genes and undruggable oncogenic drivers. Through our research, we seek to gain a more comprehensive understanding of SCLC tumorigenesis and identify new targeted therapy...

The Dana-Farber Cancer Institute seeks a Research Technician, to work in the CLL Center in Dr. Jennifer Brown’s laboratory under the Department of Medical Oncology. We seek an experienced and motivated research technician to assist with studies of the molecular mechanisms leading to the development of Chronic Lymphocytic leukemia (CLL), the most common adult leukemia of mature B lymphocytes. Primary responsibilities will include up to daily processing of CLL blood samples in sterile conditions for storage and/or experiments . The person in this position may also be frequently preparing DNA or RNA from these samples and as time allows may be able to participate in other projects in the laboratory which will allow broader experience. The Research Technician position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments...

The Sethi Laboratory at the Dana-Farber Cancer Institute and Harvard Medical School is seeking a highly motivated, creative, collegial and dedicated full-time research technician with a bachelor’s in biology or related field to join their group. Our overall goal is to combine clinical observations and patient-derived data with rigorous basic science investigation to yield opportunities for impactful translational advances. Our passion for investigative research is fundamentally dependent upon its power to generate a deeper understanding of human disease and ultimately improve patient care. We are particularly committed to defining the fundamental mechanisms underlying gastrointestinal cancers with the hope that such insight will translate into new prevention and treatment methods ( https://sethilab.dana-farber.org/ ). This position will be jointly mentored with Dr. Harshabad Singh, who is a gastrointestinal oncologist and a translational investigator at Dana-Farber Cancer Institute...

Exciting opportunity for motivated research technician to join a translational laboratory studying various aspects of cellular adaptive immunity, especially in relation to T regulatory cell characterization, function and expansion, as well as the effects of various immune manipulations. We have a history of successfully conducting basic and preclinical experiments on new biologic agents and translating them into the clinic, and currently collaborate in clinical trials studying the administration of T regulatory cells in solid organ transplant settings and in cancer. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to...

The Research Techinican will perform experiments for Dr. Brown's Labratory. The focus of research in our laboratory is to elucidate the factors underlying the action of steroid hormones, their receptors and co-regulators in hormone-dependent malignancies including breast and prostate cancer. This includes both the role of somatic mutations in the receptors and their co-regulators as well as changes in the epigenetically determined programs of gene expression controlled by these receptors. We utilize a combination of epigenomic profiling approaches such as ChIP-seq and CRISPR-based genetic screens in relevant cell culture models, model organisms and patient-derived tissues to identify key drivers of hormone dependence and potential new therapeutic targets. More recently, we have been exploring the effects of steroid hormones on the tumor immune microenvironment. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs...

This position will assist scientists in studying immune evasion mechanisms of metastatic breast cancer stem cells. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, cell culture work and animal work. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Bachelor's Degree required with a major in biology or...

The Center for Prevention of Progression (CPOP) is the first-of-its-kind clinic for patients with precursor conditions of hematologic malignancies. As part of the Hematologic Oncology Treatment Center, the Center for Prevention of Progression builds on Dana-Farber's past and ongoing research efforts for precursor conditions. The clinic evaluates individuals diagnosed with these conditions or at high risk for disease development and works with patients to manage their risk of disease progression. Our research team is committed to early detection and intervention to prevent precursor conditions from progressing to incurable blood cancers. Our center offers patients a range of clinical trials, including screening, treatment, and non-therapeutic trials that will help us to better understand and care for patients with precursor hematologic conditions. Within this context, our scientific teams play an important role in driving discovery, innovation, and translation. Our research...

We are seeking a highly motivated Research Technician to conduct basic and translational research in the field of oncology. Research Technician will work in Dr. Nikhil Munshi’s laboratory in the Jerome Lipper Multiple Myeloma center at Dana-Farber Cancer Institute. The Munshi Lab’s research studies focus on multiple myeloma and has transformed myeloma therapy and patient survival over the last decades through the identification and validation of therapeutic targets in tumor cells and bone marrow microenvironment. Current projects include studies on novel molecular mechanisms underlying myeloma pathogenesis and RNA-based approaches for the treatment of myeloma. The technician will be an integral member of our research team and will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity, including set-up and monitoring experiments, making observations, calculating and recording results. Located in Boston and the surrounding...

The Beltran lab in Dana-Farber Cancer Institute fosters a supportive environment offering excellent scope for professional growth. We provide robust mentorship for those on an academic track to pursue higher education. We also have numerous collaborations with pharmaceutical companies which provides networking opportunities and to gain transferable skillsets for industry positions. The Beltran Lab is focused on understanding mechanisms of treatment resistance in advanced prostate cancer through integration of clinical and molecular features of patients combined with preclinical modeling. We have used genomics and epigenomics to elucidate the molecular mechanisms driving lineage plasticity and evolution towards an androgen indifferent state. We are developing tissue and circulating biomarkers and novel therapeutic strategies for clinical translation. Our mission is to make discoveries that improve the way we manage and treat patients with advanced prostate cancer:...

The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology Lab that combines a broad range of laboratory techniques to study the pathways and protein complexes involved in the regulation of protein homeostasis often associated with human diseases, including cancer. Using our knowledge of the cellular degradation machinery, we use structure and computational guided approaches to develop and test new molecules that hijack the ubiquitin proteasome system for targeted protein degradation. Combining fundamental mechanistic insights with translational chemical biology research, we are pioneering new therapeutic avenues. The Fischer lab (https://fischerlab.dana-farber.org/) seeks a highly motivated individual to join the team as a Research Technician. This individual will be an important member of our research team and will be centrally involved in assisting various research projects utilizing several techniques that are fundamental to the workflow of the Fischer...

The laboratory of Benjamin Ebert, MD, Ph.D. is seeking a full-time technical research associate for a position at Dana-Farber Cancer Institute. (https://ebertlab.dana-farber.org/ ) Our lab uses a range of genomic, molecular, and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop novel therapeutic possibilities. We focus our efforts on determining the genetic drivers that result in myeloid malignancies and potentiate pre-malignant states in blood cancers. We seek an enthusiastic, and self-motivated individual who thrives in a fast-paced and challenging research environment. The candidate should feel comfortable as a part of an inclusive, diverse, and cohesive team. You should be able to draw on experience and skill to contribute to experimental design and execution, operation of laboratory instruments to conduct experiments, make scientific observations and record results, and use various analysis methods to determine...

The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. This role will support research within the Wolpin/Nowak laboratory as part of the Hale Family Center for Pancreatic Cancer Research ( http://halecenter.dfci.harvard.edu) and the Lustgarten Foundation Pancreatic Cancer Research Laboratory at Dana-Farber Cancer institute ( https://www.lustgarten.org/research/our-lab/ ). In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide...

The positions in this job family will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including...