Hospital Careers
  • Search Jobs
  • Search Profiles
  • Career Advice
  • Career Insights
  • Employers
  • Sign in
  • Sign up
  • Search Jobs
  • Search Profiles
  • Career Advice
  • Career Insights
  • Employers

55 professional staff nurse jobs found in Harrisburg, PA

Refine Search
Current Search
professional staff nurse Harrisburg, PA
Search within
50 miles
10 miles 20 miles 50 miles 100 miles 200 miles
Refine by Company Name
UPMC - University of Pittsburgh Medical Center  (49) AccentCare, Inc.  (3) Mifflin Center  (2) Geisinger Encompass Health Rehabilitation Hospital  (1)
Refine by Category
Nursing  (55) Home Health  (3) Assistant & Support  (1) Administration & Operations  (1)
Refine by State
Pennsylvania  (55)
UU
Aug 12, 2026
Professional Staff Nurse Emergency Department, UPMC Community Osteopathic
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC is hiring a Professional Staff Nurse (RN) to join our Emergency Department at the Community Osteopathic campus in Harrisburg! This is a full time, rotating shift position with an every 3rd weekend and every other holiday commitment required.  ***Final candidates will be hired on the appropriate level of the career ladder based on experience and education.  Purpose: The Professional Staff Nurse is a Registered Nurse and a member of the care delivery team. The Professional Staff Nurse is responsible to set the standards for the level and quality of care. The Professional Staff Nurse has responsibility, authority and accountability for the provision of nursing care. The Professional Staff Nurse manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication and collaboration with all team members. The role of the Professional Staff Nurse encompasses leadership, partnership, collaboration...
Nursing
UU
Aug 12, 2026
Professional Staff Nurse Emergency Department, UPMC Community Osteopathic
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC is hiring a Professional Staff Nurse (RN) to join our Emergency Department at the Community Osteopathic campus in Harrisburg! This is a full time, rotating shift position with an every 3rd weekend and every other holiday commitment required.  ***Final candidates will be hired on the appropriate level of the career ladder based on experience and education.    Purpose: The Professional Staff Nurse is a Registered Nurse and a member of the care delivery team. The Professional Staff Nurse is responsible to set the standards for the level and quality of care. The Professional Staff Nurse has responsibility, authority and accountability for the provision of nursing care. The Professional Staff Nurse manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication and collaboration with all team members. The role of the Professional Staff Nurse encompasses leadership, partnership,...
Nursing
UU
Aug 11, 2026
Sr. Professional Staff Nurse - Post Surgical Unit (Harrisburg Hospital)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
AG7 is a 42-bed post-surgical care unit dedicated to delivering high-quality, compassionate care to a diverse adult and geriatric patient population. Many admissions are planned elective surgeries, with a smaller percentage originating from the Emergency Department or direct physician referrals. AG7 specializes in orthopedic (bone, joint, and spine), general surgery, kidney transplant, and urology patients. Orthopedics, general surgery, and urology represent the unit’s primary areas of expertise. As part of UPMC, which has more than 40 years of transplant experience and national leadership in organ transplantation, AG7 supports comprehensive, patient-centered kidney transplant care grounded in clinical excellence and research advancement. The unit aligns closely with UPMC’s Bone, Joint, and Spine programs, including Joint Commission–certified hip and knee replacement and spine surgery programs at UPMC Harrisburg. Patients benefit from state-of-the-art facilities,...
Nursing
UU
Aug 11, 2026
Professional Staff Nurse - Post Surgical Unit (Harrisburg Hospital)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
AG7 is a 42-bed post-surgical care unit dedicated to delivering high-quality, compassionate care to a diverse adult and geriatric patient population. Many admissions are planned elective surgeries, with a smaller percentage originating from the Emergency Department or direct physician referrals. AG7 specializes in orthopedic (bone, joint, and spine), general surgery, kidney transplant, and urology patients. Orthopedics, general surgery, and urology represent the unit’s primary areas of expertise. As part of UPMC, which has more than 40 years of transplant experience and national leadership in organ transplantation, AG7 supports comprehensive, patient-centered kidney transplant care grounded in clinical excellence and research advancement. The unit aligns closely with UPMC’s Bone, Joint, and Spine programs, including Joint Commission–certified hip and knee replacement and spine surgery programs at UPMC Harrisburg. Patients benefit from state-of-the-art facilities,...
Nursing
UU
Aug 08, 2026
Professional Staff Nurse (GN)-MSICU (UPMC Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
This full-time MSICU Day/Night rotating position, including weekends and Holidays, is open to December 2026 & May 2027 GNs' with inpatient PCT experience! UPMC is committed to investing in nurses like you –financially, personally, and professionally –starting on day one of your career. From tackling student loans to advancing your career later in life, UPMC is the partner you need to succeed and thrive in your nursing career. Here’s how we support our nurses: Generous Sign-On Bonus (*Amount and eligibility based on type of nursing role and candidate experience) Up to five and a half weeks of Paid Time Off annually, plus seven paid holidays each year Dedicated career ladders, including a brand-new nursing career ladder added just this year, allowing you to achieve your highest potential while rewarding you for your experience and advanced education Tuition reimbursement of up to $6,000 per academic year at any accredited institution, available to...
Nursing
UU
Aug 08, 2026
Sr. Professional Staff Nurse II, BSN - Post Surgical Unit (Harrisburg Hospital)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
AG7 is a 42-bed post-surgical care unit dedicated to delivering high-quality, compassionate care to a diverse adult and geriatric patient population. Many admissions are planned elective surgeries, with a smaller percentage originating from the Emergency Department or direct physician referrals. AG7 specializes in orthopedic (bone, joint, and spine), general surgery, kidney transplant, and urology patients. Orthopedics, general surgery, and urology represent the unit’s primary areas of expertise. As part of UPMC, which has more than 40 years of transplant experience and national leadership in organ transplantation, AG7 supports comprehensive, patient-centered kidney transplant care grounded in clinical excellence and research advancement. The unit aligns closely with UPMC’s Bone, Joint, and Spine programs, including Joint Commission–certified hip and knee replacement and spine surgery programs at UPMC Harrisburg. Patients benefit from state-of-the-art facilities,...
Nursing
UU
Aug 08, 2026
Professional Staff Nurse, BSN (GN)-MSICU (UPMC Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
This full-time MSICU Day/Night rotating position, including weekends and Holidays, is open to December 2026 & May 2027 GNs' with inpatient PCT experience! UPMC is committed to investing in nurses like you –financially, personally, and professionally –starting on day one of your career. From tackling student loans to advancing your career later in life, UPMC is the partner you need to succeed and thrive in your nursing career. Here’s how we support our nurses: Generous Sign-On Bonus (*Amount and eligibility based on type of nursing role and candidate experience) Up to five and a half weeks of Paid Time Off annually, plus seven paid holidays each year Dedicated career ladders, including a brand-new nursing career ladder added just this year, allowing you to achieve your highest potential while rewarding you for your experience and advanced education Tuition reimbursement of up to $6,000 per academic year at any accredited institution, available to...
Nursing
UU
Aug 07, 2026
Professional Staff Nurse, Pediatrics/PICU (Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC Harrisburg, Pediatrics/PICU is seeking an experienced RN or newly graduated nurse to join their Night shift team! The Professional Staff Nurse is a Registered Nurse and a member of the care delivery team. The Professional Staff Nurse is responsible to set the standards for the level and quality of care. The Professional Staff Nurse has responsibility, authority and accountability for the provision of nursing care. The Professional Staff Nurse manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication and collaboration with all team members. The role of the Professional Staff Nurse encompasses leadership, partnership, collaboration and supervision. The Professional Staff Nurse establishes and maintains collaborative relationships with physicians, other health care providers, patients and their families, to achieve desired patient outcomes throughout the continuum of care. The...
Nursing
UU
Aug 07, 2026
Professional Staff Nurse, Pediatrics/PICU (Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC Harrisburg, Pediatrics/PICU is seeking an experienced RN or a newly graduated nurse to join their Night shift team!  The Professional Staff Nurse is a Registered Nurse and a member of the care delivery team. The Professional Staff Nurse is responsible to set the standards for the level and quality of care. The Professional Staff Nurse has responsibility, authority and accountability for the provision of nursing care. The Professional Staff Nurse manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication and collaboration with all team members. The role of the Professional Staff Nurse encompasses leadership, partnership, collaboration and supervision. The Professional Staff Nurse establishes and maintains collaborative relationships with physicians, other health care providers, patients and their families, to achieve desired patient outcomes throughout the continuum of care. The...
Nursing
UU
Aug 06, 2026
Professional Staff Nurse - M5 Medical Unit - Harrisburg
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
***Graduate nurses are welcome to apply!***   Main 5 is a 29-bed acute care medical unit that is dedicated to providing high quality compassionate care to a diverse adult and geriatric patient population. The majority of patients come to Main 5 through the Emergency Department with medical diagnoses related to the endocrine, integumentary, gastrointestinal, renal, respiratory and genitourinary systems. We specialize in the orientation of new graduates where you will gain valuable experience as you begin your nursing career.  You will find an environment that fosters teamwork and support, professional growth, shared decision making and a focus on a healthy work/life balance. We look forward to meeting you! UPMC is committed to investing in nurses like you – financially, personally, and professionally – starting on day one of your career. From tackling student loans to advancing your career later in life, UPMC is the partner you need to succeed and thrive in your...
Nursing
UU
Aug 05, 2026
Professional Staff Nurse, BSN, ICU UPMC Community Osteopathic
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC is hiring a Professional Staff Nurse (RN) to join our ICU team at UPMC Community Osteopathic in Harrisburg! This is a full time, days/nights rotating position with an every 3rd weekend and every other holiday requirement.    ***Final candidates will be placed on the appropriate level of the career ladder based on education and experience.   Purpose: The Professional Staff Nurse is a Registered Nurse and a member of the care delivery team. The Professional Staff Nurse is responsible to set the standards for the level and quality of care. The Professional Staff Nurse has responsibility, authority and accountability for the provision of nursing care. The Professional Staff Nurse manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication and collaboration with all team members. The role of the Professional Staff Nurse encompasses leadership, partnership, collaboration and...
Nursing
UU
Aug 05, 2026
Professional Staff Nurse, OR UPMC Community Osteopathic
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC is committed to investing in nurses like you –financially, personally, and professionally –starting on day one of your career. From tackling student loans to advancing your career later in life, UPMC is the partner you need to succeed and thrive in your nursing career. Here’s how we support our nurses: Generous Sign-On Bonus of up to $15,000* (*Amount and eligibility based on type of nursing role and candidate experience) UPMC’s Monthly Loan Repayment Program, exclusively for 2026 nursing graduates, offering $20,000* in loan repayment paid over three years (*Eligible flex full-time RN roles to receive a prorated amount) Up to five and a half weeks of Paid Time Off annually, plus seven paid holidays each year Dedicated career ladders, including a brand-new nursing career ladder added just this year, allowing you to achieve your highest potential while rewarding you for your experience and advanced education. Tuition reimbursement of up to $6,000 per academic...
Nursing
UU
Aug 05, 2026
Professional Staff Nurse, Expert, BSN Perianesthesia UPMC Community Osteopathic
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC is committed to investing in nurses like you –financially, personally, and professionally –starting on day one of your career. From tackling student loans to advancing your career later in life, UPMC is the partner you need to succeed and thrive in your nursing career. Here’s how we support our nurses: Generous Sign-On Bonus of up to $15,000* (*Amount and eligibility based on type of nursing role and candidate experience) Up to five and a half weeks of Paid Time Off annually, plus seven paid holidays each year Dedicated career ladders, including a brand-new nursing career ladder added just this year, allowing you to achieve your highest potential while rewarding you for your experience and advanced education. Tuition reimbursement of up to $6,000 per academic year at any accredited institution, available to employees and their dependents, plus discounts for UPMC employees including no cost RN-BSN/MSN options!   The Professional Staff Nurse, BSN, Expert is...
Nursing
UU
Aug 04, 2026
Professional Staff Nurse, Pediatrics/PICU (Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC Harrisburg, Pediatrics/PICU is seeking an experienced RN to join their night shift team! The Professional Staff Nurse is a Registered Nurse and a member of the care delivery team. The Professional Staff Nurse is responsible to set the standards for the level and quality of care. The Professional Staff Nurse has responsibility, authority and accountability for the provision of nursing care. The Professional Staff Nurse manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication and collaboration with all team members. The role of the Professional Staff Nurse encompasses leadership, partnership, collaboration and supervision. The Professional Staff Nurse establishes and maintains collaborative relationships with physicians, other health care providers, patients and their families, to achieve desired patient outcomes throughout the continuum of care. The Professional Staff Nurse...
Nursing
UU
Aug 02, 2026
Professional Staff Nurse, Expert (RN) - Neuro Interventional (Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
Position Detail: Full-time, 40 hours per week Schedule is 8's or 10's with overnight and weekend call with a 30-minute response time: 7:00am - 3:30pm 7:30am - 4:00pm 7:00am - 5:30pm Call schedule is currently 1 weekday and every 4th weekend   UPMC Harrisburg Neuro Interventional is currently looking to recruit an RN. This Neuro Interventional RN job consists of preforming circulating roles covering a wide variety of Neuro cases including not limited to MMA gluing, Pipeline, Stroke, Carotid intervention, Diagnostic imaging, using 3 and 4D imaging interop along with post processing, and Aneurysm coiling.    Purpose: The Professional Staff Nurse, Expert is a Registered Nurse, a member of the care delivery team, and responsible for seeking opportunities to assist in changing practice through process improvement. The Professional Staff Nurse, Expert is responsible to set the standards for the level and quality of care. The Professional Staff Nurse, Expert has...
Nursing
UU
Aug 02, 2026
Weekend Option, Professional Staff Nurse Expert, BSN, NICU (Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC Harrisburg, NICU is seeking an experienced RN to join their weekend team on a Day/Night rotation! The Professional Staff Nurse, BSN, Expert is a Registered Nurse, a member of the care delivery team, and responsible for seeking opportunities to assist in changing practice through process improvement. The Professional Staff Nurse, BSN, Expert is responsible to set the standards for the level and quality of care. The Professional Staff Nurse, BSN, Expert has responsibility, authority, and accountability for the provision of nursing care. The Professional Staff Nurse, BSN, Expert manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication, and collaboration with all team members. The role of the Professional Staff Nurse, BSN, Expert encompasses leadership, partnership, collaboration, and supervision. The Professional Staff Nurse, BSN, Expert establishes and maintains collaborative...
Nursing
UU
Aug 02, 2026
Professional Staff Nurse, Weekend Position - Post Surgical Unit (Harrisburg Hospital)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
AG7 is a 42-bed post-surgical care unit dedicated to delivering high-quality, compassionate care to a diverse adult and geriatric patient population. Many admissions are planned elective surgeries, with a smaller percentage originating from the Emergency Department or direct physician referrals. AG7 specializes in orthopedic (bone, joint, and spine), general surgery, kidney transplant, and urology patients. Orthopedics, general surgery, and urology represent the unit’s primary areas of expertise. As part of UPMC, which has more than 40 years of transplant experience and national leadership in organ transplantation, AG7 supports comprehensive, patient-centered kidney transplant care grounded in clinical excellence and research advancement. The unit aligns closely with UPMC’s Bone, Joint, and Spine programs, including Joint Commission–certified hip and knee replacement and spine surgery programs at UPMC Harrisburg. Patients benefit from state-of-the-art facilities,...
Nursing
UU
Aug 02, 2026
Professional Staff Nurse, Expert, BSN-Acute Care Cardiac (UPMC Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
We are hiring an experienced RN or GN for this full-time Day/Night rotating position, including weekends & Holiday rotation.  Acute Care Cardiac (Main 7) is a 44 bed acute care cardiac unit dedicated to providing high-quality, compassionate care to a wide variety of patients. Our patient population consists of those with multiple comorbidities with a specialization in heart failure. All of our patients are provided continuous telemetry monitoring and may require cardiac drips to maintain stable cardiac care. Although our unit is fast paced, it is a great place to learn time management skills, assessment skills, and critical thinking ability. We have a mix of experienced and new nurses who are committed to caring for our patients as well as each other. This is a great learning environment where our staff supports teamwork, interdisciplinary team building, shared governance, and professional growth. Thank you for taking the time to learn about Main 7 and we hope you are...
Nursing
UU
Aug 02, 2026
Professional Staff Nurse, Expert, BSN-MSICU (UPMC Harrisburg)
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
This full-time MSICU Day/Night rotating position, including weekends and Holidays, is open to experienced RNs and GNs' with inpatient PCT experience! UPMC is committed to investing in nurses like you –financially, personally, and professionally –starting on day one of your career. From tackling student loans to advancing your career later in life, UPMC is the partner you need to succeed and thrive in your nursing career. Here’s how we support our nurses: Generous Sign-On Bonus (*Amount and eligibility based on type of nursing role and candidate experience) Up to five and a half weeks of Paid Time Off annually, plus seven paid holidays each year Dedicated career ladders, including a brand-new nursing career ladder added just this year, allowing you to achieve your highest potential while rewarding you for your experience and advanced education Tuition reimbursement of up to $6,000 per academic year at any accredited institution, available to employees and...
Nursing
UU
Aug 02, 2026
Professional Staff Nurse CG2 Neurology UPMC Community Osteopathic
UPMC - University of Pittsburgh Medical Center Harrisburg, PA
UPMC is hiring a full time Professional Staff Nurse to join our Neurology unit at our Community Osteopathic campus in Harrisburg! This is a full time, night shift position working every third weekend and every other holiday.    ***Final candidates will be placed on the appropriate level of the career ladder based on experience and education.    Purpose: The Professional Staff Nurse is a Registered Nurse and a member of the care delivery team. The Professional Staff Nurse is responsible to set the standards for the level and quality of care. The Professional Staff Nurse has responsibility, authority and accountability for the provision of nursing care. The Professional Staff Nurse manages and provides patient care activities for a group of patients and their families through the application of independent judgment, communication and collaboration with all team members. The role of the Professional Staff Nurse encompasses leadership, partnership, collaboration and...
Nursing
  • General
  • About Us
  • Contact Us
  • Terms of Use
  • Privacy Policy
  • Employers
  • Explore Plans
  • Find Talent
  • Solutions
  • Learn More
  • Sign Up
  • Candidates
  • Search Jobs
  • Post Profile
  • Nurse Scholarship
  • Best Hospitals
  • Connect
  • Facebook
  • Twitter
  • LinkedIn
© 2025 MedBlast, Inc. All Rights Reserved.