34 postdoctoral research fellow jobs found in Boston, MA

Postdoctoral Fellow in Computational RNA Biology and Cancer A postdoctoral fellow position is available in the Insco Laboratory in the Department of Medical Oncology at Dana-Farber Cancer Institute (DFCI). We are seeking an enthusiastic and highly motivated scientist to join our team! The Insco Lab investigates how aberrant RNA processing and defects in nuclear RNA quality control contribute to cancer, with a particular focus on melanoma. We are especially interested in the dark transcriptome, including aberrant RNAs derived from repetitive genomic elements and mis-spliced transcripts. By combining zebrafish models, mechanistic studies in human melanoma cell lines, and analyses of patient-derived datasets, we seek to uncover clinically relevant RNA-driven oncogenic mechanisms and identify therapeutic vulnerabilities in high-risk melanoma. Our lab fosters a culture of curiosity, rigor, collaboration, and teamwork. Each scientist leads an independent project while benefiting from...

The Wachter Lab seeks a highly motivated individual to join the team as a POSTDOCTORAL RESEARCH FELLOW who will work on biochemistry and structural biology projects addressing fundamental questions in our understanding of molecular mechanisms of transcriptional control. While we consider various backgrounds, a strong interest in understanding how molecular machines work and the desire to tackle a major problem of great significance are absolutely essential. The Wachter Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology lab that combines molecular biology, structural biology, functional genomics and proteomics to study mechanisms of transcriptional regulation associated with human diseases, including cancer. The Wachter lab integrates structural biology, molecular biology and computational guided approaches to address fundamental questions about the mechanistic principles of transcription. Our laboratory is based at Dana-Farber Cancer Institute in Longwood...

The Uppaluri lab in the Department of Medical Oncology is seeking an intelligent, creative and collegial post-doctoral research fellow to join our group. We perform pre-clinical mouse modeling and human translational work towards identifying and targeting genomic and immunologic dependencies to improve head and neck cancer patient outcomes. Our group has expertise in carcinogen induced oral cancer models and in performing first in class immune and small molecule therapeutic clinical trials. Research areas in our lab include cancer genome discovery, CRISPR screening, investigation of tumor microenvironment and T cell biology using high-dimensional methodologies (scRNAseq, spatial proteomics/transcriptomics), development and study of novel oncogene-inducible and carcinogen-based oral cancer models and analysis of patient samples from ongoing clinical trials to define molecular correlates of response, improved therapeutic targeting strategies and new biological insights.   We are a...

Post-doctoral position available in the laboratory of Dr. Geoffrey Shapiro at the Dana-Farber Cancer Institute and Harvard Medical School. The fellow will engage in studies of cyclin-dependent kinase (CDK) inhibitors in models of ER+ breast cancer and other CDK4-dependent cancers, with an overarching theme of reversing CDK inhibitor resistance. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers,...

The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology lab that combines molecular biology, computational biology, structural biology and chemistry with various ‘Omics’ techniques such as proteomics to study the pathways and protein complexes involved in protein homeostasis and the ubiquitin proteasome system often associated with human diseases, including cancer. The Fischer lab integrates structural biology, molecular biology and computational guided approaches to address fundamental questions about the mechanistic principles that govern signaling through the ubiquitin proteasome system. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to...

The Mills Lab at Dana-Farber Cancer Institute and Harvard Medical School is seeking a highly motivated Postdoctoral Fellow in Immunology/Metabolism to investigate metabolite signaling and innate immune cell function in models of infection and cancer. Our research uses mass spectrometry-based approaches to define metabolite signaling at both the cellular and whole-body level, with the goal of understanding how metabolism shapes immune cell function. We are looking for an individual with a strong interest in metabolomics, immunology, and translational discovery who is excited to contribute to a collaborative and intellectually vibrant research environment. The successful candidate will join a dynamic team of international researchers, including PhD students and postdoctoral fellows, who value collaboration, scientific rigor, and mutual support. The lab provides substantial one-on-one mentorship, along with the guidance and resources needed for successful project completion and...

The Postdoctoral Research Fellow will work under the direction of Dr Mary-Ellen Taplin, MD. The position will work collaboratively with faculty in DFCI GU Medical Oncology to support projects involving a GU pathologist. These projects include prostate, bladder, kidney and testis cancer. Dr. Taplin’s research program is centered on clinical and translational investigations in genitourinary oncology, with a strong focus on prostate cancer, including localized high-risk disease and metastatic castration-resistant prostate cancer. The fellow will contribute to pathology-focused translational research efforts in GU Oncology trials investigating novel treatment strategies, biomarker development and mechanisms of response and resistance in cancer trials. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related...

The Dana-Farber Cancer Institute seeks a Post-Doctoral Computational Biologist in the Gillani Lab in Computational Pediatric Cancer Research (https://gillanilab.dana-farber.org/). The Post-Doctoral Computational Biologist will work on the analysis of genomic, transcriptomic, and epigenomic datasets with the goal of arriving at new insights around targetable biology and clinical biomarkers to advance the care of pediatric cancer patients. The mission of the Gillani Lab is to advance pediatric, adolescent, and young adult cancer care using cutting-edge computational biology approaches. We strive to understand the germline genetics and tumor genomics of pediatric cancer to inform novel approaches to treatment. We value great science that matters to patients, caring about each other as people and colleagues, and fostering an environment of mutual respect and collaboration. The qualified candidate will design and lead projects grounded in data analysis in the domain of computational...

The Xin Gu Laboratory (https://labs.dana-farber.org/xingulab/) at Dana-Farber Cancer Institute (Department of Cancer Biology) and Harvard Medical School (Department of Cell Biology) seeks highly motivated postdoctoral research fellows to investigate fundamental mechanisms of protein turnover and their roles in physiology and disease. The Gu Lab is an interdisciplinary laboratory studying how cells control protein homeostasis. We combine discovery-driven approaches including genetic screening and proteomics with mechanistic biochemistry and structural biology as well as in vivo animal models to uncover and characterize previously unknown cellular pathways. Our goal is to understand these mechanisms from the molecular level to their physiological functions and relevance to human disease. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of...

The lab of Dr. Irene Ghobrial is seeking a highly motivated Postdoctoral Research Fellow to conduct computational research and lead projects focusing on multiple myeloma and its precursor conditions. Based on the mission of the Ghobrial lab, the successful candidate will be responsible for identifying novel biomarkers for tumor burden, tumor biology, and immune state in both the bone marrow and peripheral blood aiming to improve assessment for prognostication and monitoring of therapy response in patients with monoclonal gammopathy of unknown significance (MGUS) and smoldering multiple myeloma (SMM). In pursuit of these goals, the successful applicant will leverage human sample data continuously generated in the lab for multi-omic analysis (including genomic, transcriptomic, and proteomic), including samples derived from clinical trials. The successful candidate will work at the intersection of computational biology, genomics, proteomics, pathology, artificial intelligence, and...

The lab of Dr. Irene Ghobrial is seeking a highly motivated Postdoctoral Research Fellow to conduct laboratory-based research and lead projects focusing on multiple myeloma and its precursor conditions. Based on the mission of the Ghobrial lab, the successful candidate will be responsible for identifying novel biomarkers for tumor burden, tumor biology, and immune state aiming to improve prognostication and monitoring of therapy response in patients with precursor conditions, including monoclonal gammopathy of unknown significance (MGUS) and smoldering multiple myeloma (SMM). In pursuit of these goals, the successful applicant will leverage next-generation technologies and advanced laboratory methods, including scRNA-seq, single-cell genomic characterization, spatial proteomics/transcriptomics, proteomics, flow sorting, and immunohistochemistry among others. In addition, the application and integration of stat-of-the-art genomic, spatial, and proteomic technologies will be key...

Dr. Vokler Hovestadt is hiring a Postdoctoral Research Fellow- Biostatistics/Machine Learning for his lab! The Hovestadt Lab in the Department of Pediatric Oncology at Dana-Farber Cancer Institute (https://hovestadtlab.github.io, affiliations with Boston Children’s Hospital and the Broad Institute of MIT and Harvard) is seeking a highly motivated computational postdoctoral research fellow. Our lab studies childhood brain tumors and leukemias, two of the most common cancers in children. We aim to better understand tumor biology using cutting-edge experimental and computational approaches. Translational goals of our research include the development of more accurate patient classification systems and novel treatment strategies. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to...

Dr. Volker Hovestadt is seeking a Postdoctoral Research Fellow - Computational Genomics to join his team. The Hovestadt Lab in the Department of Pediatric Oncology at Dana-Farber Cancer Institute (https://hovestadtlab.github.io, affiliations with Boston Children’s Hospital and the Broad Institute of MIT and Harvard) is seeking a highly motivated computational postdoctoral research fellow. Our lab studies childhood brain tumors and leukemias, two of the most common cancers in children. We aim to better understand tumor biology using cutting-edge experimental and computational approaches. Translational goals of our research include the development of more accurate patient classification systems and novel treatment strategies. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to...

The Nicolson lab at is seeking a highly motivated, PhD (or equivalent) graduate who will support our laboratory as a Postdoctoral Research Fellow in the Department of Radiation Oncology at Dana-Farber Cancer Institute and Harvard Medical School, with a focus on radioligand therapy (RLT), molecular imaging, and radiation biology. Research in the Nicolson lab spans radioligand therapy (RLT), fluorescence and radiopharmaceutical in vivo imaging, combination therapies, and the biological effects of radiation- and radionuclide-induced DNA damage. This work integrates expertise across radio-, nano-, and synthetic chemistry, molecular biology, radiobiology, and bioengineering. We are seeking an enthusiastic and independent researcher interested in applying multidisciplinary approaches to radioligand therapy, molecular imaging, combination therapies, and radiation biology. The ideal candidate will thrive in a collaborative and dynamic environment and be motivated to develop their expertise...

The Cancelas/Singh Laboratory at Dana-Farber Cancer Institute seeks a highly motivated Postdoctoral Scientist to study hematopoietic stem cell biology and blood formation in health and disease. Our research spans signal transduction, mitochondrial biology, stem cell aging, inflammation, bone marrow regeneration, clonal hematopoiesis, and interactions between hematopoietic cells and the bone marrow microenvironment. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate...

The Reinherz lab at Dana-Farber Cancer Institute and Harvard Medical School is recruiting a postdoctoral fellow to study HIV-1 vaccine immunology. We use an interdisciplinary approach combining structural biology, molecular biology, biochemistry, and immunology to generate insights that can be translated into HIV-1 vaccine design. Specific research areas of interest include molecular and cellular mechanisms underlying B cell immunodominance and strategies to modulate B cell affinity maturation during vaccination to induce protective immunity while preventing induction of autoimmunity. The laboratory provides a rich training environment and access to cutting-edge techniques. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment...

The Haq lab is recruiting for a highly motivated and capable Research Fellow to join the Haq Lab at Dana-Farber Cancer Institute. The successful candidate will have a strong interest in cancer biology and therapeutics and will function as part of a multidisciplinary basic science and translational team. This post-doctoral position is available to start at any time. The focus of the research will be to study the mechanisms of metastasis and dormancy in uveal melanoma. We have generated a novel mouse model that closely resembles the disease, yielding numerous insights into it. This is quite novel work, and the incoming post-doc will play a major role in authoring papers based on findings already gathered within our group. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an...

The Dana-Farber Cancer Institute seeks a POSTDOCTORAL RESEARCH FELLOW, under the Van Allen lab (http://vanallenlab.dana-farber.org/) to work on the analysis of new datasets generated in the context of multiple clinically oriented cancer sequencing projects in order help advance efforts for precision cancer medicine. As Dr. Van Allen is the Chief of the Division of Population Sciences, our research effort includes collaborative work with the division faculty members on identification of cancer risk, risk mitigation, early detection, prevention, delivery of cancer care and health policy. The Van Allen lab is an interdisciplinary and highly collaborative laboratory with diverse scientists from various scientific domains leading exciting cancer research. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related...

When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives. Has been awarded or has completed the requirements for a doctoral degree or foreign equivalent. Is a trainee pursuing advanced studies beyond the doctoral level in preparation for an independent career in a biomedical field. In collaboration with and under the mentorship of the Principal Investigator (PI), a Research Fellow engages in activities that will further his or her professional development. Job Description: Primary Responsibilities: - Abides by the institutional policies of BIDMC relating to health and safety, equality of opportunity and data storage and management. (essential) - As a member of the research team, actively pursues research under the supervision of a principle investigator while developing skills for independent work. (essential) - Receives training in and performs duties contributing to the investigational work of the team...

When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives. Position Overview The Mavrikaki Lab at Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School is seeking a highly motivated and creative junior Postdoctoral Research Fellow to lead high-impact studies investigating the molecular mechanisms driving brain aging and cognitive decline. Our laboratory integrates spatial transcriptomics, multi-omic approaches, advanced molecular biology, and in vivo mouse models to resolve key pathways underlying brain aging. Building upon our recent landmark work—including spatial transcriptomic and microRNA atlases of the adult lifespan human prefrontal cortex—the successful candidate will drive research exploring how specific cell populations regulate age-related cognitive function. Key Responsibilities • Multi-Omics & Molecular Profiling: Design and execute multi-omic pipelines (including spatial transcriptomics...