51 laboratory jobs found in Boston, MA

Job Ref:47410 Location:27 Dry Dock Ave, Boston, MA 02210 Category:Imaging Employment Type:Full time Work Location:Remote: 100% off site Overview Dana-Farber Cancer Institute (DFCI) is seeking a SPECT/PET/CT Imaging Specialist (In Vivo) to support the cancer research activities at the Lurie Family Imaging Center (LFIC).  The LFIC is a state-of-the-art 14,000-square foot preclinical imaging facility, equipped with preclinical in vivo imaging capabilities, including Positron Emission Tomography (PET), Single-Photon Emission Computed Tomography (SPECT), Computed Tomography (CT), Ultrasound Imaging (US), Optical Imaging (BLI/ FLI), and image-guided radiation therapy, in order to support investigators with their research programs and studies using innovative and relevant imaging strategies. The interdisciplinary in vivo translational and experimental therapeutics studies conducted at the LFIC are focused on cancer, with an emphasis on in vivo...

Job Ref:47172 Location:27 Dry Dock Ave, Boston, MA 02210 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview Dana-Farber Cancer Institute (DFCI) is seeking a highly motivated Pre-Clinical Scientist to support the research activities at the Experimental Therapeutics (ETx) Core and the Lurie Family Imaging Center (LFIC).  The ETx Core and LFIC are co-located in a state-of-the-art 14,000 square-foot preclinical facility, fully equipped with housing and procedure rooms, as well as a suite of in vivo imaging scanners. The Pre-Clinical Scientist will integrate with a highly skilled team of Scientists and Research Associates, and report directly to the Director. The in vivo studies conducted at the facility are focused on cancer research, with an emphasis on in vivo pharmacology, the assessment of novel cancer therapeutics, and multimodality imaging of cancer, and provide key information for the...

Job Ref:45918 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The role of the Laboratory Manager is to both assist with ongoing experiments of Dr. Beltran and other members of the Beltran Lab and manage the lab's daily operations. The Laboratory Manager is expected to maintain a high level of organization and accountability in this highly visible role. This position will ensure compliance with all regulatory requirements; review laboratory protocols of all research groups (internal and external); maintain laboratory spaces and equipment; and act as a liaison between staff and key stakeholders. Additionally, the Specialist will have the opportunity to learn and utilize a variety of research techniques and be able to co-author publications when appropriate.  The Beltran Lab primarily focuse s on understanding mechanisms of treatment resistance in...

Job Ref:47421 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 4-5 days onsite/week Overview A computationally-oriented team led by Rameen Beroukhim and Simona Dalin at the Dana-Farber Cancer Institute and Broad Institute seeks an associate computational biologist to join in efforts to develop and apply cutting-edge genomic algorithms and analyses to characterize genomic rearrangements in cancers and normal tissues, and better understand how errors in double strand break (DSB) repair result in these rearrangements. This individual will contribute to a lively team and wider community of laboratory scientists, computational biologists, cancer geneticists, and software engineers dedicated to discovering and understanding the alterations in the cancer genome and discovering cancer vulnerabilities that could lead to new therapeutics. We are looking for a person who wants to...

Job Ref:47414 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview Dana-Farber Cancer Institute is seeking an experienced PhD-level scientist to join the antibody discovery and antibody-based therapeutics development-focused LAUNCHPAD or the L ab for A ntibody and N anobody P hage Display and D iscovery. A pre-clinical strategic center, LAUNCHPAD’s mission is to streamline “discovery to translation” of antibody-based immunotherapies for cancer. The LAUNCHPAD team works closely with academic partners to design experimental strategies to identify promising antibody ‘hits’ as well as engineering hits to generate potential therapeutic bispecific and CAR T-cell immunotherapies. The candidate should be an exceptionally motivated individual with a passion for working in multidisciplinary teams to design, screen and engineer immunotherapy candidates and advance...

Job Ref:47376 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview  A  RESEARCH TECHNICIAN position is available in the laboratory of Dr. Yana Pikman ( https://pikmanlab.dana-farber.org/ ) at the Dana-Farber Cancer Institute. Our research focuses on the application of clinical genomics for development of targeted therapy approaches for acute leukemia, drug testing and combination screening with the ultimate goals of 1) improving understanding of leukemia biology and 2) translating bench discovery to clinical care. You will join a team of investigators leading these efforts in the academic environment, working at the bench, collaborating closely with scientists as well as clinical researchers. You will play an essential, and possibly leading, role in project-focused work. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute...

Job Ref:47413 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview Dana-Farber Cancer Institute is seeking a research technician to join the L ab for A ntibody and N anobody P hage Display and D iscovery (LAUNCHPAD), a pre-clinical research group with the mission to streamline “discovery to translation” of antibody-based immunotherapies for cancer. The LAUNCHPAD team works closely with DFCI PIs to implement the discovery and functional screening of antibody ‘hits’ as well as the engineering of hits to generate potential therapeutic antibody-based biologics and cell therapies. The candidate should be motivated to learn and execute workflows for antibody discovery via in vitro display as well as the production, screening, and characterization of candidate antibody and CAR T cell therapies.  Additionally, another key aspect of this role will be to work...

Job Ref:46697 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Administration Employment Type:Full time Work Location:Hybrid: 2-3 days onsite/week Overview The Senior Research Administrator for the Division of Molecular and Cellular Oncology (MCO) and the Center for Cancer Genomics (CCG) oversees the research portfolios of multiple laboratories, exercising independent judgment while keeping the supervisor, Department Director, and Center leadership informed. In this role, you will partner with faculty and investigators to develop competitive sponsored research applications and manage the financial health of sponsored and institutional funds across operating, federal, industry, foundation, donor, institutional, and clinical trial sources. You will provide senior-level financial planning and management, lead operational process improvements, and cultivate strong business relationships with Cancer Genomics leadership (Directors and...

Job Ref:47386 Location:450 Brookline Ave, Boston, MA 02215 Category:Clinical Research Employment Type:Full time Work Location:Onsite: 4-5 days onsite/week Overview The Translational Research Project Manager I (TRPM I) oversees the daily coordination and management of translational and biobanking Breast Oncology research projects, which involves collecting various biological samples and clinical data. This role supports grant applications, progress reports, project initiation, regulatory compliance, and patient identification for research projects. The TRPM I bridges clinical and laboratory research by supporting both types of investigators. Additionally, the TRPM I indirectly supervises research coordinators and independently manages a portfolio of projects for each investigator. The specific tasks and responsibilities of the TRPM I vary based on departmental and investigator needs. This position’s work location is  onsite at our main...

Job Ref:47390 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Murakami Laboratory seeks a motivated technician candidate passionate about clinically relevant scientific discovery to participate in translational research in lymphoma and leukemia. A critical responsibility of this position is processing blood, bone marrow, and tissue specimens from patients with blood cancers treated on early phase clinical trials and to isolate specific tumor and immune cell populations for single-cell molecular and functional interrogation. The candidate will work with the laboratory’s data scientists to maintain accurate records of these specimens to facilitate biomarker analyses. The candidate will also generate patient-derived model systems for functional validation and preclinical experimental therapeutics studies. Finally, the candidate will contribute to an...

Job Ref:47337 Location:450 Brookline Ave, Boston, MA 02215 Category:Nursing Employment Type:Full time Work Location:Onsite: 4-5 days onsite/week Overview The Research Nurse in collaboration with the physician, is responsible for the implementation and evaluation of clinical research in their specific program/area.  The CRN has expert knowledge of cancer as a disease process, cancer treatment modalities (or comparable knowledge for a non-oncology area, e.g. infection control) and the process of conducting medical clinical research.  In addition, the CRN utilizes evidence-based nursing practice and has expertise in developing and coordinating a plan of care designed to meet the physical, psychological, and social needs of those cancer patients and their families undergoing therapy in a clinical research trial.  Strong interpersonal, organizational and communication skills are required.  Knowledge of current literature and a commitment to continued...

Job Ref:47328 Location:450 Brookline Ave, Boston, MA 02215 Category:Clinical Research Employment Type:Full time Work Location:Onsite: 4-5 days onsite/week Overview The Gastrointestinal (GI) Oncology Clinical Research Program at Dana-Farber Cancer Institute is seeking a Clinical Research Coordinator (CRC) to join our program. The GI Oncology Clinical Research Program supports PI initiated, industry sponsored, and cooperative group phase I - IV clinical trials across multiple GI cancers, including esophageal, stomach, liver, pancreas, colon, and neuroendocrine. The Clinical Research Coordinator work within the clinical research program and support the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator. The CRC will be responsible for the primary data collection and management of patient clinical information as it pertains to participation in clinical trials....

Job Ref:47292 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The laboratories led by Rameen Beroukhim and Bill Kaelin seek a research assistant to spearhead collaborative, translational projects to find new ways to treat brain cancers. This project is also being led by an experienced MD-PhD physician-scientist who will provide day-to-day mentorship about both experimental and analytic strategies to move the projects forward and career development. Both Drs. Beroukhim and Kaelin are also physician scientists who will provide similar mentorship on a weekly to biweekly basis. The experiments involve a combination of high-throughput functional genomics, descriptive genomics, and work with both cell line and mouse model systems, and are aimed to identify new therapeutic targets in brain cancers that are currently always fatal. We are looking for a person...

Job Ref:47216 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Lead Animal Technologist reports directly to the Animal Resources Facility (ARF) Technical Services Manager or Technologist Supervisor. The Lead Animal Technologist provides animal clinical care and treatment to research animals as prescribed by the ARF Technical Services (TS) Manager or Technologist Supervisor and as directed by the Attending Veterinarian. Under the direction of the TS Manager/Supervisor may be responsible for packing and shipping sentinel animals to Charles River Laboratories for diagnostic testing. Must be able to sex and wean mice, and identify animals by ear punch, ear tag number or toe clip. Will perform injections (IV, IP, SC, IM, ID), blood sampling techniques as  assigned by (TS) Manager or (PT) to TS projects. Located in Boston and the surrounding communities,...

Job Ref:47266 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 4-5 days onsite/week Overview A team of researchers led by Rameen Beroukhim and Simona Dalin seeks a research technician to develop and apply molecular biology techniques with the goal of understanding how improper double strand break (DSB) repair results in genomic rearrangements, particularly in cancer. These projects include developing new methods to assess patterns of rearrangements across the genome and to apply these methods to understand how different cancers differ in their mutational processes and resulting evolutionary trajectory.     We are looking for a person who will lead their projects, think ing independently and making original intellectual contributions. We welcome all levels of input from research technicians, including input on the conduct of...

Job Ref:47254 Location:450 Brookline Ave, Boston, MA 02215 Category:Clinical Research Employment Type:Full time Work Location:Hybrid: 2-3 days onsite/week Overview The Research Data Specialist (RDS) will support the Breast Oncology Cohort Studies program under the auspices of the Principal Investigators, Director, and Research Manager, in the areas of clinical data collection and collation of biospecimens - specifically related to patients with germline mutations in the Department of Breast Oncology. Duties may include but are not limited to; the examination, synthesis, and evaluation of medical records; the abstraction and recording of pertinent medical information; and the organization and collation of biospecimens collected within cohort studies. Position will work with investigators working on research studies focused on germline mutations (e.g. BRCA1/2) within Breast Oncology. Additional responsibilities will include the following:...

Job Ref:46921 Location:450 Brookline Ave, Boston, MA 02215 Category:IT/Informatics Employment Type:Full time Work Location:Onsite: 4-5 days onsite/week Overview A computationally-oriented team led by Rameen Beroukhim and Simona Dalin at the Dana-Farber Cancer Institute and Broad Institute seeks a computational associate to join in efforts to develop and apply cutting-edge genomic technologies to characterize genomic rearrangements in cancers and normal tissues, and better understand how errors in double strand break (DSB) repair result in these rearrangements. Projects include 1) identifying sequence features that influence the formation of genomic rearrangements based on data from thousands of tumors and matched normal samples, 2) applying sophisticated statistical approaches to determine relationships between the presense of specific rearrangements and genetic/pharmacologic vulnerabilities in cancer cell lines, and 3) developing new analysis...

Job Ref:47171 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Bandopadhayay and Beroukhim Labs ( www.bandolab.org and www.beroukhimlab.org) at DFCI (with co-affiliations with Boston Children’s Hospital and the Broad Institute) are seeking a joint Lab Manager to join our efforts to find better treatments for children and adults diagnosed with brain tumors. We apply cutting-edge genomic technologies to identify drivers of childhood and adult cancers, identify strategies to target these and to determine mechanisms of resistance to current and novel treatments. The aim of these efforts is to perform translational research to develop new therapies to improve outcomes of children diagnosed with these tumors. The work will be highly translational and span efforts from profiling the cancer genomes of pediatric brain tumors to determining new therapeutic...

Job Ref:47149 Location:450 Brookline Ave, Boston, MA 02215 Category:Administration Support/Customer Service Employment Type:Full time Work Location:Hybrid: 2-3 days onsite/week Overview The Cellular Therapies Donor Services Specialist facilitates allogeneic donor identification and collection processes on behalf of adult and pediatric patients undergoing a stem cell transplant or other Cellular Therapy, including standard of care and clinical research therapies. This position is responsible for initiating and managing the search for suitable donors, coordinating donor testing and collection, donor product acquisition, and ensuring a smooth and effective process for both the donor and recipient. The role requires collaboration with multidisciplinary care teams, and donor registry organizations, as well as attention to detail, organization, problem-solving and effective communication. The specialist is responsible for the analytical, logistical, and...

Job Ref:47240 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Belfer Center for Applied Cancer Science is an integrative research center within Dana-Farber Cancer Institute. Our mission is to enhance and accelerate oncology drug discovery & development through bridging of academia, industry, and clinical research. We apply industrial capabilities to cutting edge academic/clinical science. We partner with industry in drug discovery/development & work with industrial partners to delineate the clinical path of novel therapies for cancer patients. This integrated, goal-oriented organization represents a new academic construct that provides an unprecedented opportunity to change the way anti-cancer therapeutics are discovered and developed. For more information please visit: http://belfercenter.dfci.harvard.edu/ Located in Boston and the...