9 Laboratory Technicians jobs found

Job Ref:47292 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The laboratories led by Rameen Beroukhim and Bill Kaelin seek a research assistant to spearhead collaborative, translational projects to find new ways to treat brain cancers. This project is also being led by an experienced MD-PhD physician-scientist who will provide day-to-day mentorship about both experimental and analytic strategies to move the projects forward and career development. Both Drs. Beroukhim and Kaelin are also physician scientists who will provide similar mentorship on a weekly to biweekly basis. The experiments involve a combination of high-throughput functional genomics, descriptive genomics, and work with both cell line and mouse model systems, and are aimed to identify new therapeutic targets in brain cancers that are currently always fatal. We are looking for a person...

Job Ref:47266 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 4-5 days onsite/week Overview A team of researchers led by Rameen Beroukhim and Simona Dalin seeks a research technician to develop and apply molecular biology techniques with the goal of understanding how improper double strand break (DSB) repair results in genomic rearrangements, particularly in cancer. These projects include developing new methods to assess patterns of rearrangements across the genome and to apply these methods to understand how different cancers differ in their mutational processes and resulting evolutionary trajectory.     We are looking for a person who will lead their projects, think ing independently and making original intellectual contributions. We welcome all levels of input from research technicians, including input on the conduct of...

Job Ref:47120 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Research Technician will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity.  In general, they will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.    The D’Andrea Lab investigates the mechanisms underlying chromosome instability and cancer susceptibility. Our research focuses on the molecular signaling pathways that regulate the DNA damage response in mammalian cells. Disruption of these pathways—whether through germline or somatic mutations—can lead to genomic instability, sensitivity to ionizing radiation, and defects in cell cycle checkpoints and DNA repair. Such alterations are frequently observed in...

Job Ref:47006 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview Pre-clinical group developing next generation antibody and CAR T cell immunotherapies for cancer is looking for an exceptionally motivated individual with past in vivo experience. The Smith Lab group is focused CAR T cell immunotherapy for cancer and protein engineering/synthetic biology; taking projects from conception to transgene design /genetic engineering, through reduction to practice, and into in vivo studies, and ultimately to the clinic. >10 clinical trials have launched stemming from the Smith team’s pre-clinical work. The candidate will make substantial contributions to the leadership of our in vivo work among other contributions. This will include coordinating and advising other senior staff in the lab in terms of design and timelines for in vivo experimentation, planning,...

Job Ref:46857 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Hybrid: 2-3 days onsite/week Overview The Dana-Farber Cancer Institute seeks a Laboratory Scientist to focus on next-generation, translational pathology studies who will work within the Wolpin-Nowak laboratory ( https://labs.dana-farber.org/wolpin-nowaklab/ ) as part of the Hale Family Center for Pancreatic Cancer Research ( https://labs.dana-farber.org/halecenter ) and the Lustgarten Foundation Pancreatic Cancer Research Laboratory at the Dana-Farber Cancer institute. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and...

Job Ref:46765 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Targeted Protein Degradation (TPD) Proteomics Core within the Fischer Lab at Dana-Farber Cancer Institute serves as a resource for the Cancer Biology Department, aiding investigators in answering key research questions using mass spectrometry-based proteomics. We employ quantitative chemoproteomic and interactomic approaches to identify drug targets and are continuing to expand our repertoire to meet the needs of our core users. Our core is equipped with extensive mass spectrometry equipment including timsTOF HT, timsTOF Ultra2 and Orbitrap Eclipse tribrid mass spectrometers. The TPD Proteomics Core seeks a highly motivated individual to join the team as a at Dana-Farber Cancer Institute is seeking an experienced RESEARCH TECHNICIAN, who will employ mass spectrometry-based...

Job Ref:45906 Location:450 Brookline Ave, Boston, MA 02215 Category:Fellowships Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology lab that combines molecular biology, computational biology, structural biology and chemistry with various ‘Omics’ techniques such as proteomics to study the pathways and protein complexes involved in the regulation of protein abundance via the ubiquitin proteasome system that are often associated with human diseases, including cancer. The Fischer lab integrates structural biology, molecular biology and computational guided approaches to address fundamental questions about the mechanistic principles that govern signaling through the ubiquitin proteasome system.   Our laboratory is based at Dana-Farber Cancer Institute in Longwood Center and is an affiliate of the BCMP department at Harvard Medical School. We...

Job Ref:45508 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview https://labs.dana-farber.org/fischerlab/ The Targeted Protein Degradation (TPD) Proteomics Core within the Fischer Lab at Dana-Farber Cancer Institute serves as a resource for the Cancer Biology Department, aiding investigators in answering key research questions using mass spectrometry-based proteomics. We employ quantitative chemoproteomic and interactomic approaches to identify drug targets and are continuing to expand our repertoire to meet the needs of our core users. Our core is equipped with extensive mass spectrometry equipment including timsTOF HT, timsTOF Ultra2 and Orbitrap Eclipse tribrid mass spectrometers. The TPD Core seeks a highly motivated individual to join the team as a Senior Research Technician, who will employ mass spectrometry-based technologies to assess the...

Job Ref:45509 Location:450 Brookline Ave, Boston, MA 02215 Category:Research Laboratory Employment Type:Full time Work Location:Onsite: 100% onsite Overview The Targeted Protein Degradation (TPD) Proteomics Core within the Fischer Lab at Dana-Farber Cancer Institute serves as a resource for the Cancer Biology Department, aiding investigators in answering key research questions using mass spectrometry-based proteomics. We employ quantitative chemoproteomic and interactomic approaches to identify drug targets and are continuing to expand our repertoire to meet the needs of our core users. Our core is equipped with extensive mass spectrometry equipment including timsTOF HT, timsTOF Ultra2 and Orbitrap Eclipse tribrid mass spectrometers. The TPD Core seeks a highly motivated individual to join the team as a Research Scientist I, who will employ mass spectrometry-based technologies to assess the cellular proteome in response to external stimuli. This...