Dana-Farber Cancer Institute
Boston, MA, USA
Job Ref:43782
Location:450 Brookline Ave,
Boston,
MA 02215
Category:Fellowships
Employment Type:Full time
Work Location:Onsite: 100% onsite
Overview
The Reinherz lab at Dana-Farber Cancer Institute and Harvard Medical School is recruiting a research associate in a post-doctoral position to study CD8 T-cell targeting of human tumor cells via immunopeptidome shift technologies in conjunction with novel T cell receptor (TCR) mechanobiology. This approach is predicated on the recent understanding that TCR performance in mediating ligand recognition and cytolytic function is 1) dependent on physical load emanating from cellular motion during immune surveillance and 2) truncal neoantigens are generally poorly if at all expressed. This new knowledge will allow us to circumvent cognate recognition impediments that foster tumor escape naturally. We use an...
Research
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