UCLA Health Los Angeles, CA, USA
Description This is an exciting opportunity for a technically minded person who enjoys working in a lab-based environment to provide support for ongoing mass spectrometry and proteomics projects. We are looking for a motivated Staff Research Associate II to work on a variety of projects with the laboratory to identify critical molecular targets in malignant gliomas and develop novel, brain-penetrant small molecule therapeutics to treat these brain cancers. Projects require application of a variety of quantitative methodologies, including proteome-wide protein expression and post-translational modification profiling to fully characterize biological systems, chemical proteomics approaches to determine drug mechanisms of action, and targeted quantification of drug concentrations in brain tissues and blood plasma. The main duties include routine sample preparation, advanced UHPLC-MS method development and optimization, as well as operation and maintenance of state-of-the-art LC-MS...