20 computational biologist jobs found in Boston, MA

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. We seek an enthusiastic and highly motivated bioinformatics associate to join our cancer genomics research group. This individual will join oncologists, computational biologists and research scientists on our effort aimed at studying the causes and consequences of cancer. This position will provide ample opportunities for...

The Department of Breast Oncology at Dana-Farber Cancer Institute seeks a Computational Biologist to work on the generation of DNA sequencing, RNA sequencing and epigenetic sequencing datasets in the context of multiple clinically oriented studies in order to help advance efforts for precision cancer medicine. The Computational Biologist, in collaboration with faculty leaders in our breast cancer genomics efforts, principal investigators, and senior director of cohort and translational studies, will be involved in cross-disciplinary efforts to generate large clinically-annotated datasets describing genetic changes across breast cancer and to develop sophisticated statistical and computational approaches to analyze and interpret these data. The aim of these efforts will be to characterize mutations, programs and evolutionary dynamics that contribute to therapeutic response and resistance. These new data could help identify novel approaches for personalized care in oncology. In...

The Computational Biologist I is responsible for routine data analysis or processing of biological data, with a focus on high-throughput technologies and genomic databases. The Computational Biologist is a quantitative scientist who collaborates with scientific investigators and with other research staff in the analysis of high-throughput data, and dissemination of scientific results. The Computational Biologist may work on many types of projects and areas of research including cancer genomics, functional genomics, immuno-oncology, molecular imaging, data management and integration, and querying biological databases. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to...

The Raghavan Laboratory at the Dana-Farber Cancer Institute (DFCI) and Harvard Medical School is seeking a highly motivated and collaborative full-time computational biologist with a Bachelor’s or Master’s degree in Computational Biology, Bioinformatics, Biology, Biomedical Engineering, or related field to join the group. The Raghavan lab investigates how tumor cell states shape cancer cell behaviors, microenvironmental interactions, and therapeutic sensitivity and resistance, with a primary focus in pancreatic and biliary cancers. We apply a variety of techniques including genomic, RNA, and single-cell sequencing of patient samples and cell models, high throughput drug testing, and CRISPR engineering with the long-term goal of identifying new state- and context-specific cancer vulnerabilities. We work closely with clinicians in the Gastrointestinal Cancer Center at DFCI to combine clinical observations and patient-derived data with rigorous basic science investigation to identify...

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The Fischer Lab (https://fischerlab.dana-farber.org/) at Dana-Farber Cancer Institute is a Structural and Chemical Biology Lab that combines molecular biology, computational biology, structural biology and chemistry with various ‘Omics’ techniques to study the pathways and protein complexes involved in the regulation of...

A B.S. or M.S. in bioinformatics, mathematical, physical, or computer science, or comparable research experience, together with significant experience in computer programming and computational biological applications. A strong background in statistics and biology. Experience managing and curating large datasets and with machine learning techniques desired. Excellent oral and written communication skills and the ability to perform both self-directed and guided research are required. Must demonstrate outstanding personal initiative and the ability to work effectively as part of a team. Ability to meet deadlines and efficiently multitask is a must. Excellent oral and written communication skills with the ability to effectively collaborate across a range of knowledge (e.g. effective communication with software developers and physicians). Experience in R and/or Python is preferred, with willingness to learn new languages and tools as the field grows (e.g. Github, Docker, WDL, etc). At...

The Computational Biologist II is responsible for complex data analysis or processing of biological data, with a focus on high-throughput technologies and genomic databases. The Computational Biologist is a quantitative scientist who collaborates with scientific investigators and with other research staff in the analysis of high-throughput data, and dissemination of scientific results. The Computational Biologist may work on many types of projects and areas of research including cancer genomics, functional genomics, immuno-oncology, molecular imaging, data management and integration, and querying biological databases. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to...

Overview: The Qi laboratory at the Dana-Farber Cancer Institute is looking for exceptional Postdoctoral Fellows in cancer biology (qi lab website: qilab.dana-farber.org). The Qi lab studies gene regulatory pathways using the emerging discipline of chemical biology. Successful candidates will work with an interdisciplinary team of scientists including medicinal chemists, biochemists, computational biologists, and cancer biologists to develop novel inhibitors of chromatin modifying enzymes, such as methyltransferases, demethylases and bromodomains. The successful candidate will perform research that will help make fundamental insights to cancer biology using novel small molecule inhibitors to gain mechanistic understanding in cancer therapy. We expect that novel therapeutics for human clinical investigation will emerge directly from these efforts through academic/industry collaborations. The postdoctoral fellow will be affiliated with the Department of Cancer Biology at Dana-Farber...

A postdoctoral fellow position is available to join the Hill Laboratory (https://hilllab.dana-farber.org/) in the Department of Medical Oncology at Dana-Farber Cancer Institute. We are looking for an enthusiastic fellow to work on our existing and upcoming projects. Our group studies the way ovarian and endometrial cancers respond to therapy and how the entire tumor changes over time, especially with respect to DNA damage repair defects in the tumor cells. We utilize complex ex vivo models of these tumors containing a full complement of tumor and normal cells to understand drug response and tumor evolution in real time. We aim to more fully characterize how evolving DNA damage repair defects in tumors cells change the entire tumor response to different therapies and lead to complex mechanisms of therapy resistance; develop methods to combat this resistance; and utilize our findings to design and implement better treatments in these deadly forms of women’s cancer. Located in Boston...

Lead Research Technician - Bing Center for Waldenstrom’s macroglobulinemia Located in the heart of the Boston medical area, the Treon Lab in the Bing Center for Waldenstrom’s macroglobulinemia (BCWM) within the Dana Farber Cancer Institute is a multi-disciplinary team of scientists, and computational biologists dedicated to the advanced developments of novel therapeutics and genomic discoveries for the lymphoplasmacytic lymphoma called Waldenstrom’s macroglobulinemia. The BCWM laboratory uses a variety of biochemical, cell biology, and translational approaches to identify new therapeutic targets and develop preclinical models. The position offers the opportunity to lead research efforts for high-throughput analyses and routine laboratory tasks. For more information on the Center and its background please visit our dedicated website at www.bingcenterforwm.org A full-time position is available for an enthusiastic, initiative-taking individual who can thrive in a fast-paced,...

The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of physician scientists, scientists and computational biologists at the Dana-Farber Cancer Institute and the Broad Institute. Our laboratory uses genomics and a range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop novel therapeutics. Our specific focus is to understand the role of chromatin modifiers and find novel therapeutic opportunities in myeloid malignancies, including myelodysplastic syndromes and acute myeloid leukemia. A full-time Senior research technician position is available in the laboratory of Zuzana Tothova, MD, Ph.D. at Dana-Farber Cancer Institute. Visit our website: https://tothovalab.dana-farber.org/ We are seeking enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging research environment, and can interact well with others as part of a cohesive team. If you have a desire to make a...

A full-time Laboratory Operations Manager position is available in the laboratory of Zuzana Tothova, MD, Ph.D. at Dana-Farber Cancer Institute. We are seeking enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging research environment, and can interact well with others as part of a cohesive team. If you have a desire to make a significant impact in healthcare and have the fortitude to work hard, you will succeed within this team. This is an ideal position for someone who enjoys being in the world of cutting-edge laboratory research. A growth mindset and a willingness to take on challenging learning opportunities will be sought out traits. Ideal candidates will possess strong interpersonal skills along with a desire to help others to succeed. The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of physician scientists, scientists and computational biologists at the Dana-Farber Cancer Institute and the Broad Institute. Our laboratory uses...

The Freedman laboratory at Dana-Farber Cancer Institute and Harvard Medical School studies how the noncoding genome contributes to cancer pathogenesis and progression. Our work is characterized by asking questions of biological and clinical significance and deploying the appropriate tools to rigorously test these hypotheses. We use a variety of molecular biology, statistical, genomic, and epigenomic approaches to understand cancer. If required, we develop novel technology. Our research is highly collaborative and includes laboratory investigators, clinical investigators, and computational biologists. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all...

The Aguirre laboratory at Dana-Farber Cancer Institute and Harvard Medical School studies the genetics and biology of gastrointestinal (GI) cancers, particularly pancreatic cancer. We utilize variety of molecular biology and genomic approaches to understand GI cancer with three major focus areas: 1) Discovery and validation of the new therapeutic targets in GI cancers; 2) Investigating RAS biology and targeting in pancreatic cancer; and 3) Understanding the genetic and phenotypic subtypes of pancreatic cancer using single cell genomic and transcriptomic analysis of tumor biopsies and patient-derived organoid models. Research in the laboratory ranges from basic mechanistic investigation of cancer gene function or novel small molecule therapeutics to highly translational genomic and functional studies of patient-derived tissues from clinical trials. The Aguirre lab works collaboratively within the Dana-Farber Hale Center for Pancreatic Research (https://halecenter.dfci.harvard.edu/),...

The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of physician scientists, scientists and computational biologists at the Dana-Farber Cancer Institute. Our laboratory uses genomics and a range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop novel therapeutics. Our specific focus is to understand the role of chromatin modifiers and epigenetic factors and find novel therapeutic opportunities in myeloid malignancies, including myelodysplastic syndromes and acute myeloid leukemia. A full-time Staff scientist position is available in the laboratory of Zuzana Tothova, MD, Ph.D. at Dana-Farber Cancer Institute. We are seeking enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging research environment, and can interact well with others as part of a cohesive team. If you have a desire to make a significant impact in healthcare and have the fortitude to work...

The Aguirre lab at Dana-Farber Cancer Institute is a basic and translational oncology laboratory with a focus on gastrointestinal cancers, such as pancreatic cancer. We utilize a variety of genomic, functional genetic and molecular biology approaches to identify novel therapeutic strategies in pancreatic cancer and to test these strategies in patient-derived models or genetically engineered mouse models of the disease. We actively collaborate with clinical oncologists, surgeons, pathologists, geneticists and computational biologists to perform multi-disciplinary translational research. We are in search of a highly motivated and capable Senior Research Technician to join the Aguirre lab at Dana-Farber Cancer Institute to work with both animal models and organoid of pancreatic cancer and to test new therapeutic strategies in these models. The successful candidate will have a strong interest in cancer biology and therapeutics and will function as part of a multidisciplinary basic...

A full-time post-doctoral fellow position is available in the laboratory of Dr. Jens Lohr at the Dana-Farber Cancer Institute for a highly motivated postdoctoral fellow to join our translational and basic research efforts. Our research focuses on the application of genomic approaches and single cell technologies to cancer therapy discovery with the ultimate goals of 1) Deciphering mechanisms of drug resistance in multiple myeloma and other types of lymphoid malignancies, 2) Understanding the basic biology of circulating tumor cells, exosomes and cell-free DNA in the evolution of cancer, and 3) Translating bench discovery to clinical care. Dana Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to...

The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of scientists, physician-scientists and computational biologists at the Dana-Farber Cancer Institute. Our laboratory uses genomics and a wide range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders, with the aim of translating these insights into novel therapies for patients with cancer. Our specific focus is to understand the role of chromatin modifiers and epigenetic factors during disease progression of blood cancers, and to find novel therapeutic opportunities in myeloid malignancies, including myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). A full-time postdoctoral fellow position is available in the laboratory of Zuzana Tothova, MD, Ph.D. at Dana-Farber Cancer Institute (https://tothovalab.dana-farber.org/). We are a seeking enthusiastic, collegial, creative, self-motivated individual who thrives in a fast-paced,...

The Aguirre lab at Dana-Farber Cancer Institute is a basic and translational oncology laboratory within the Hale Center for Pancreatic Cancer Research. We utilize a variety of genomic, functional genetic and molecular biology approaches to identify novel therapeutic strategies in pancreatic cancer and to test these strategies in patient-derived models or genetically engineered mouse models of the disease. We actively collaborate with clinical oncologists, surgeons, pathologists, geneticists and computational biologists to perform multi-disciplinary basic and translational research. We are in search of a highly motivated and capable Research Technician to join the Aguirre laboratory as part of an interdisciplinary effort to identify new drug targets for pancreatic cancer and to evaluate new therapeutic strategies in patient-derived organoid models of pancreatic cancer. The successful candidate will have a strong interest in cancer biology and therapeutics and will function as part...

The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of physician scientists, scientists and computational biologists at the Dana-Farber Cancer Institute and the Broad Institute. Our laboratory uses genomics and a range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop novel therapeutics. Our specific focus is to understand the role of chromatin modifiers and epigenetic factors and find novel therapeutic opportunities in myeloid malignancies, including myelodysplastic syndromes and acute myeloid leukemia. A full-time animal technical research associate position is available in the laboratory of Zuzana Tothova, MD, Ph.D. at Dana-Farber Cancer Institute. We are seeking enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging research environment, and can interact well with others as part of a cohesive team. If you have a desire to make a significant impact in...